Chordoma of the Spine A Comprehensive Review 2021 Original pdf

This book provides a comprehensive review of the epidemiology, pathogenesis, diagnosis, and management of chordomas of the mobile spine and sacrum. Historically, knowledge about how to deliver such state-of-the-art care has not been widespread, resulting in inconsistent treatment, and, all too often, suboptimal outcomes for chordoma patients. This text is an important step towards broadening that knowledge, and, in turn, improving the care provided to chordoma patients. The book is divided into 4 parts comprising 16 chapters. The first part focuses on the pathophysiology and molecular drivers of chordoma. The second focuses on the epidemiology and clinical history, as well as the histological, oncologic, and radiographic work-up of chordoma. The third part focuses primarily on the technical aspects of surgery for chordoma. It is broken down by anatomic region, with the final two chapters focusing on the soft tissue and bony reconstruction following chordoma resection. The last part focuses on the exciting field of adjuvant therapies for chordoma. This includes both radiation therapies and novel chemotherapeutic options for recurrent, metastatic, and dedifferentiated chordoma.