Provides insights into drug discovery innovations that are shaping future central nervous system (CNS) therapies.
Within the broad field of neuroscience, drug discovery targeting the central nervous system (CNS) presents both extraordinary opportunities and complex challenges. Disorders such as Alzheimer’s disease, schizophrenia, and epilepsy affect millions of people worldwide and require innovative treatment strategies. However, understanding brain processes and overcoming the blood-brain barrier continue to pose significant obstacles for researchers and developers.
Trends in Drug Discovery in the CNS provides a comprehensive overview of the approaches, successes, and challenges shaping this vital area of drug research. Covering a broad range of key areas, from current treatment paradigms to emerging technologies, this cutting-edge book brings together the expertise of leading scientists and drug developers to address the role of cannabinoids and psychotropics in advancing CNS therapies, discusses emerging approaches such as protein disintegrators and allosteric modulators, examines funding strategies and university-industry collaborations, highlights advances in brain-invasive cancer therapies and other impactful areas, and more.
Reviews advanced methods, including biomarkers, animal models, and brain imaging, for central nervous system drug discovery. Explores innovative therapies such as combination drugs and prodrugs to improve treatment outcomes. Analyzes the challenges of targeting diseases such as Alzheimer’s and schizophrenia with novel therapeutic strategies. Includes real-world case studies that illustrate achievements and lessons learned in the development of central nervous system drugs.
Trends in Central Nervous System Drug Discovery is a vital reference for academic researchers and industry professionals in medicinal chemistry, drug discovery, and neurobiology, and is also an ideal resource for graduate courses in neuroscience or pharmaceutical sciences.