Presenting an illuminating exploration into the intricate interplay between aluminum and neurotoxicity, this book emerges as a testament to cutting-edge research and scholarly discourse. Aiming to bridge the gaps in our understanding, this text delves into the fusion of scientific literature and original research, unraveling the links between aluminum exposure, cognitive decline, and Alzheimer’s Disease (AD).
Salient Features:
Delving into Distribution: Explores aluminum’s intricate journey within the brain, unraveling its region-specific and subcellular distribution
Interrogating Pathology: Maps aluminum’s association with the pathological hallmarks of AD, such as neurofibrillary tangles and amyloid beta accumulation
Tracing Mechanisms: Uncovers the molecular mechanisms underlying aluminum’s role in oxidative stress, cell death, apoptosis, and necroptosis
Dynamics of Brain Function: Explores aluminum’s influence on electrophysiological variation and synaptic plasticity
Pioneering Perspectives: Examines aluminum’s contested role in AD, genetic susceptibility interactions, and its impact on epigenetic modifications and non-coding RNAs
Updated and Expanded: The second edition features updated chapters and enriching content on AD-like pathological traits, nanoparticles’ neurotoxic effects, and more
This comprehensive volume stands as an invaluable resource, systematically synthesizing the intricate facets of aluminum neurotoxicity. Ideal for researchers, scholars, and practitioners, it reshapes our comprehension of this multifaceted nexus and reinforces our quest for innovative solutions.
