This comprehensive guide delves into every facet of atherosclerosis, exploring everything from human pathology to experimental studies, and bridging basic science with clinical application. The book consists of 20 detailed chapters that cover essential topics, including the human pathology of atherosclerosis, cellular biology (focusing on endothelial cells, smooth muscle cells, monocyte/macrophages, dendritic cells, and more), and an in-depth look at the molecular biology of lipid metabolism and hyperlipidemia. It also addresses the pathophysiology of acute coronary syndrome, plaque vulnerability, and the implications of aortic aneurysms and peripheral atherosclerosis.
The opening chapters present the history of atherosclerosis, followed by various hypotheses that shape our understanding of this condition. Readers will gain access to cutting-edge information, drawing from human pathological evidence, experimental animal studies, and practical clinical insights. With over 100 vibrant color images and clear schematic illustrations, the book juxtaposes real pathological observations with their clinical significance, enhancing understanding.
This resource is invaluable not only for researchers and clinicians seeking to grasp the molecular underpinnings of atherosclerosis but also for guiding them toward addressing unresolved questions based on the authors’ extensive expertise. It serves as an essential reference for medical students eager to gain knowledge about cardiovascular diseases or those planning to engage in atherosclerosis research.
